"But she’s not just vivid and generously expressive; she has become, in her last few roles, a high-flying actress who reveals everything that’s inside her characters. Through sheer conviction, she makes the defiant-dying-girl tearjerking clichés work. And her sex scenes with Gyllenhaal are the most intimate and erotic glimpses of romantic love that we’ve seen in American movies in years. The two of them lounge naked in bed, talking, making love, finessing a scene of Jamie’s impotence that could have been embarrassing but becomes genuinely funny. “Love and Other Drugs” has many weak spots, but what it delivers at its core is as indelible as (and a lot more explicit than) the work of such legendary teams as Clark Gable and Joan Crawford, Spencer Tracy and Katharine Hepburn."

David Denby’s review of “Anne Hathaway’s Breasts and Other Drugs.”